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Download Analytical method development and validation by uv and hplc techniques: UV,HPLC,Dissolution methods epub

by Hajera Khan,Shahed Mirza,Faria Khan




Gemifloxacin,a flouroquinoline derivative has antibacterial activity. Ambroxol dibromoaminobenzyl derivatives have mucolytic activity.GEM and AMB are available in tablet dosage form (G-cin A,Lupin)for mucolytic action. The present work dealt with simultaneous estimation of GEM and AMB from bulk and tablet formulation by different UV spectrophotometric, RPHPLC and Dissolution techniques. Five UV methods were developed which are accurate, precise, rapid and economical for the estimation of GEM and AMB in Tablet dosage form. The developed HPLC method was validated in terms of accuracy, repeatability, and precision. A good linear relationship was observed for GEM An attempt has been made to carry out the dissolution study of the marketed formulation by applying four established UV-Visible Spectrophotometric methods for estimation of % release of the drug (GEM & AMB).
Download Analytical method development and validation by uv and hplc techniques: UV,HPLC,Dissolution methods epub
ISBN: 3659247979
ISBN13: 978-3659247972
Category: Science
Subcategory: Mathematics
Author: Hajera Khan,Shahed Mirza,Faria Khan
Language: English
Publisher: LAP LAMBERT Academic Publishing (December 20, 2012)
Pages: 124 pages
ePUB size: 1956 kb
FB2 size: 1561 kb
Rating: 4.2
Votes: 340
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