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Download The Baboon in Biomedical Research (Developments in Primatology: Progress and Prospects) epub

by John L. VandeBerg,Sarah Williams-Blangero,Suzette D. Tardif




Nonhuman primates have played critical roles in biomedical research, and they are among the few animals whose use in research continues to increase. The scienti?c value of nonhuman primates derives from their close phylogenetic proximity to man and their consequent anatomic, physiologic, and genetic similarities to man. Only nonhuman primates can provide adequate models for many complex physiological and disease processes of humans. The baboon is a relative newcomer to the repertoire of nonhuman primates used in biomedical research. However, in less than 50 years since its ?rst use in the U. S. , it has become one of the most popular laboratory primate species. It is larger than the other widely used monkey species, making it advantageous for many types of experiments and technological developments. It is extraordinarily hardy and highly fecund in captivity. It closely resembles humans in a variety of physiological and disease processes, such as cholesterol metabolism, early stages of atherosclerosis, and alcoholic liver disease. Its chromosomes closely resemble those of humans, and many genes of the two species lie in the same chromosomal order. Among all primates, baboons are the most widely used models for the genetics of susceptibility to complex diseases and they are the ?rst nonhuman primate for which a framework genetic linkage map was established. In addition, the baboon genome is currently being sequenced, and as a result the utility of this species for biomedical research will be dramatically increased.
Download The Baboon in Biomedical Research (Developments in Primatology: Progress and Prospects) epub
ISBN: 0387759905
ISBN13: 978-0387759906
Category: Science
Subcategory: Biological Sciences
Author: John L. VandeBerg,Sarah Williams-Blangero,Suzette D. Tardif
Language: English
Publisher: Springer; 2009 edition (November 21, 2008)
Pages: 392 pages
ePUB size: 1973 kb
FB2 size: 1258 kb
Rating: 4.9
Votes: 410
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